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Precursor Fat Cells May Shed Light on Diseases

To understand more about the mystery of obesity, it's important to understand how fat cells are born, nurtured and matured. And the enlightenment that will flow from understanding obesity may sweep away mysteries relating to the generation of cardiovascular disease and diabetes, which seem to be so much more prevalent among people who are obese.

So it was with delight that scientists greeted a recent study identifying precursor cells that develop into full-blown fat tissue. The research, performed on "skinny" mice genetically modified to have no fat deposits, showed that injecting one particular type of cell into the mice caused them to form fat.

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Another Five Predictors of Long Life

Being conscious of fat and sugar in your diet, and working out at the gym, may seem like the keys to a long and healthy life. But you may easily tire of calorie counting and workouts. It seems the real signs of whether you will be blessed with considerable longevity is if you've adopted certain lifelong healthy lifestyles and attitudes - some of which you can still start.

Here are five of them.

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Researchers Control "Hunger Hormone"

Investigators may have found a novel route to weight loss by controlling the hormone that produces appetite.

The hormone, ghrelin, is produced by the fundus, or upper part of the stomach. Since ghrelin requires a rich supply of blood to be created, the scientists shut down the blood supply to that area of the stomach by chemically blocking the main artery there.

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Healthy Feet Incompatible With Fat

Obesity can lead to foot amputations, warns a podiatry organization in Australia.

This is "particularly [true of] those patients who have diabetes, because they can lose feeling in their feet and sustain injuries, which can get infected and sometimes require amputation," said Brenden Brown, vice president of the Australasian Podiatry Council. And, he said, most people are completely unaware of the feet-fat connection.

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Chocolate Milkshakes Shed Insight on Obesity

The journal "Science" reports on the impact of chocolate milkshakes on obese people versus non-obese people.

The Oct. 17 issue of the journal "Science" reports on the impact of chocolate milkshakes on obese people versus non-obese people. Chocolate milkshakes in particular were studied because: "There are very few things that excite the brain as much as chocolate." So says researchers at the Oregon Research Institute and the University of Oregon, where the study was conducted.

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Calorie Overload Creates Brain Imbalances

Overeating can cause the brain to lose control and cause damage potentially leading to diabetes, heart disease, and other ills - according to new U.S. research.

Eating too much appears to make a usually dormant immune system pathway in the brain, sending out immune cells to attack and destroy non-existent invaders. The finding could help explain why obesity causes so many different diseases, and also may offer a way to prevent obesity itself.

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Five Foods to Slim By

Instead of getting on a fad diet, only to crash and burn a few weeks later, it's best to eat wholesome, natural foods in five or so small meals a day, according to anti-aging expert Dr. Maoshing Ni.

Dr. Mao, as the doctor of Chinese medicine and author of the best-selling book Secrets of Longevity is known, says a good weight-loss diet includes lean proteins, such as chicken breast; legumes, such as split peas and lentils; and whole grains, fruits, and vegetables. Fad diets, he says, almost inevitably deny a person some important nutrients, leading to cravings all too often cause the dieter to regain his weight - and perhaps even more. He advocates eating the following as part of a sensible weight-loss program:

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Alternatives to Cholesterol-Lowering Drugs

If you have high cholesterol and you're brimming with confidence in synthetic pharmaceuticals, then statin drugs such as Lipitor, Crestor, Zocor and Levitor are for you.

If, however, you lean toward medicating your body with natural products, there are a variety of items that have been scientifically proven to lower cholesterol - without the serious side effects of statin drugs that include severe memory loss, muscle cramps, liver toxicity, hair loss, heartburn and nausea.

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Seven Breakthrough Strategies for Weight Loss

Sixty-six percent of Americans are overweight, and 32 percent are obese, so many citizens have now gotten serious about losing weight. But many times a dieter or exerciser can hit a weight-loss plateau that's seemingly impossible to get beyond.

Therefore, here follows seven areas to focus on to flank excess weight and, hopefully, lead to big improvements in health.

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How Obesity Abets Type 2 Diabetes

Human fat can be healthy or sick - healthy in lean people and sick in obese. And a new research effort shows sick fat cells can produce proteins that contribute to type 2 diabetes.

The study, performed by researchers at Temple University, discovered that fat cells in obese people bear a great deal of stress in a cellular component called the endoplasmic reticulum, which is the cells' protein factory. The stress, says lead researcher Dr. Guenther Boden, apparently produces proteins connected with insulin resistance, a major contributor to obesity-related diabetes. In particular, 19 proteins were more abundant in obese people's fat cells than lean people's, including three that were related to a specific endoplasmic reticulum stress-related response.

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